| Registro completo |
| Provedor de dados: |
OAK
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| País: |
Japan
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| Título: |
Some Bovine proteins behave as dietary fibres and reduce serum lipids in rats
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| Autores: |
Ruvini, Liyanage
Hashimoto, Naoto
Han, Kyu-Ho
Kajiura, Teppei
Watanabe, Shoko
Shimada, Ken-ichiro
Sekikawa, Mitsuo
Ohba, Kiyoshi
Fukushima, Michihiro
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| Data: |
2007
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| Ano: |
2007
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| Palavras-chave: |
Bovine Dietary proteins
Serum lipids
Dietary Fibres
Hepatic mRNAs
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| Resumo: |
We examined the physiological importance of bovine dietary proteins in rats fed diets prepared from bovine Achilles’tendons and arteries. Rats were fed for 4 weeks, with 20% casein diet (CON), in comparison with two diets containing 15% casein and 5% of either bovine Achilles’ tendons (AC) or arteries (AR) protein preparations. The serum total cholesterol concentration and non-HDL cholesterol level in the AR fed group were significantly lower (P<0.05) than those in the CON fed group at the end of the 4 week feeding period. The hepatic mRNAs were measured, and the HMG-CoA reductase mRNA level was significantly lower (P<0.05) in AR fed group compared to CON fed group. Total hepatic cholesterol concentration, in rats fed AC was significantly (P<0.05) higher than in the CON fed group. The serum triglyceride (TG) concentration and fatty acid synthase (FAS) mRNA level in AC and AR fed groups were significantly lower (P<0.05) compared to the CON fed group through out the feeding period. Faecal neutral sterol excretion was significantly (P<0.05) higher in the AC and AR fed groups compared to the CON fed group. The results of this study demonstrate that the some bovine dietary proteins have similar functions as dietary fibres which lowered the serum lipid concentration by enhancing faecal neutral sterol excretion, or suppressing lipid synthesis in the liver. Moreover, favourable amino acid compositions in AR and AC may also have an effect on low plasma lipid concentration in bovine protein diets fed groups.
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| Idioma: |
Inglês
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| Identificador: |
http://ir.obihiro.ac.jp/dspace/handle/10322/745
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| Editor: |
CABI
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| Formato: |
application/pdf
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